The Multifaceted Benefits of DHEA 

It’s time to dive into a topic that has generated a lot of buzz in the fitness and health community: the testosterone-supporting benefits of DHEA.

If you're keen on optimizing your health, performance, and perhaps even your hormone levels, this is an ingredient you should be very interested in. Below, I break down the science, benefits, and considerations surrounding DHEA supplementation.

Understanding DHEA

DHEA, or dehydroepiandrosterone, is a hormone produced naturally in the body by the adrenal glands, with smaller amounts coming from the brain and gonads. It serves as a precursor molecule, or prohormone, for sex hormones including testosterone and estrogen. This makes DHEA a critical component in how women produce testosterone and offers a backup method for men to bolster their testosterone levels.

The Link Between DHEA and Testosterone

The primary allure of DHEA supplements lies in their potential to support  testosterone levels.* This notion is backed by several studies, such as a 2018 French research paper that observed a significant testosterone increase in both young men and women following DHEA supplementation. Further, a comprehensive 2020 review concluded that DHEA can indeed elevate testosterone levels, especially in women, when dosed above 50 milligrams per day.

DHEA's benefits stretch far beyond just supporting  testosterone. Research also points to DHEA's role in supporting healthy cholesterol and blood insulin levels, supporting muscle strength, and even supporting  immune function and psychological well-being.* 

Who Should Consider DHEA Supplementation?

Given the legal status of prohormones, including DHEA, in many countries, my advice primarily targets those residing in the United States where DHEA remains legal, and for those who are not competitive athletes (as DHEA is banned for athletes in most countries). Individuals over 40 might find DHEA particularly beneficial due to its myriad health benefits, even if direct testosterone elevation isn't observed. Younger individuals looking for energy level and sexual wellness support might also benefit from DHEA supplementation.*

Optimal DHEA Supplementation Practices

DHEA supplements are typically available in 25mg or 50mg amounts, though higher amounts  can also be found. Based on my experience and the existing literature, I recommend starting with 50 to 100 milligrams of DHEA twice per day, adjusting as necessary to find what works best for you.

My brand-new Alpha X hormone support product contains 50mg of DHEA per recommended two daily servings, which puts you in the range of the aforementioned 50-100-milligram window. My original Alpha JYM formula does not contain DHEA, so I recommend Alpha X for anyone looking to reap the potential benefits of this ingredient. 

Bottom Line on DHEA

DHEA is a supplement that offers more than just testosterone support; it's about enhancing overall health and vitality, especially as we age. While it may not be a magic bullet for everyone, the broad range of benefits it may provide makes it worth considering. As always, ensure to consult with a healthcare professional before starting any new supplement regimen.

References:

Collomp, K., et al. Effects of short-term DHEA intake on hormonal responses in young recreationally trained athletes: modulation by gender. Endocrine 59(3):538-546, 2018.

Li, Y., et al. A dose response and meta-analysis of dehydroepiandrosterone (DHEA) supplementation on testosterone levels: perinatal prediction of randomized clinical trials. Exp Gerentol 2020.

Morales, A. J., et al. The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf) 49(4):421-432, 1998.

Rabijewski, M., et al. Positive effects of DHEA therapy on insulin resistance and lipids in men with angiographically verified coronary heart disease - preliminary study. Endokrynol Pol 56(6):904-910, 2005.

Rutkowski, K., et al. Dehydroepiandrosterone (DHEA): hypes and hopes. Drugs 74(11):1195-1207, 2014.

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